Lhermitte-Duclos disease and pregnancy


  • Artur Franko
  • Izidora Holjar-Erlić
  • Damir Miletić
  • Oleg Petrović


Background. Lhermitte-Duclos disease or dysplastic gangliocytoma of the cerebellum is a rare disorder that can cause progressive mass effects to the structures occupying posterior fossa. Magnetic resonance imaging is a diagnostic modality of choice demonstrating characteristic non-enhancing gyriform pattern with the enlargement of cerebellar folia, hypointense on T1 and hyperintense on T2 weighted magnetic resonance images.

Case report. The authors present a case of 37-year old woman with previously unknown Lhermitte-Duclos disease in the third trimester of pregnancy from the first signs of the disease to the first six months after delivery.

Conclusions. More experience will be needed with this disease in pregnancy and post delivery period to recommend pregnancy for women with such condition. However, this case shows that a pregnant woman with Lhermitte-Duclos disease could reach full-term pregnancy and deliver a healthy child, without lifethreatening risk.

Author Biographies

Artur Franko

Izidora Holjar-Erlić

Damir Miletić

Oleg Petrović




How to Cite

Franko, A., Holjar-Erlić, I., Miletić, D., & Petrović, O. (2006). Lhermitte-Duclos disease and pregnancy. Radiology and Oncology, 40(1). Retrieved from https://www.radioloncol.com/index.php/ro/article/view/1272