Definitive radiotherapy for cervix cancer: long term results for patients treated between 1998-2002 at the Institute of Oncology Ljubljana

Authors

  • Helena Barbara Zobec Logar Onkološki inštitut Ljubljana
  • Barbara Segedin
  • Robert Hudej
  • Primoz Petric

Abstract

Abstract

Background. Brachytherapy (BT) for cervix cancer worldwide, is despite three-dimensional (3D) era, still based on a two-dimensional (2D) approach, utilizing point A for the prescription of the tumor dose. This report summarizes results of 2D cervix cancer practice at the Institute of Oncology Ljubljana. Methods. 98 patients were analysed. The influence of age, hemoglobine level, histology, grade, stage, lymph node status, cumulative point A dose, and overall treatment time on survival and local control (LC) were evaluated. Acute and late side effects were assesed. Results. 5 and 8-year overall survival (OS), disease specific survival (DSS) and LC rate were as follows: 47.2 % and 43.0%, 54.7 % and 53.4 %, 74.9 % and 72.5 %, respectively. Point A dose, positive lymph nodes and histology of the tumor influenced LC or survival. Probability of grade three and four late complications in the first five years was 7.1 % for gastrointestinal tract and 3.3 % for genitourinary system and vagina. Conclusions. Point A dose, histology and lymph node status are independent predictors of survival or LC.

Author Biographies

Helena Barbara Zobec Logar, Onkološki inštitut Ljubljana

Barbara Segedin

Robert Hudej

Primoz Petric

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Published

2013-08-27

How to Cite

Zobec Logar, H. B., Segedin, B., Hudej, R., & Petric, P. (2013). Definitive radiotherapy for cervix cancer: long term results for patients treated between 1998-2002 at the Institute of Oncology Ljubljana. Radiology and Oncology, 47(3). Retrieved from https://www.radioloncol.com/index.php/ro/article/view/1491

Issue

Section

Clinical oncology