Impact of respiratory motion on breast tangential radiotherapy using the field-in-field technique compared to irradiation using physical wedges

Abstract

Background: This study aimed to evaluate whether the field-in-field (FIF) technique is more vulnerable to the impact of respiratory motion than irradiation using physical wedges (PWs).

Patients and methods: Ten patients with early stage breast cancer were enrolled. Computed tomography (CT) was performed during free breathing (FB). After the FB-CT data set acquisition, 2 additional CT scans were obtained during a held breath after light inhalation (IN) and light exhalation (EX). Based on the FB-CT images, 2 different treatment plans were created for the entire breast for each patient and copied to the IN-CT and EX-CT images. The amount of change of in the volume of the target receiving 107%, 95%, and 90% of the prescription dose (V107%, V95%, and V90%, respectively), on the IN-plan and EX-plan compared with the FB-plan were evaluated.

Results: The V107%, V95%, and V90% were significantly larger for the IN-plan than for the FB-plan in both the FIF and PW plans. While the amount of change in the V107% was significantly smaller in the FIF than in the PW plan, the amount of change in the V95% and V90% was significantly larger in the FIF plan. Thus, the increase in the V107% was smaller while the increases in the V95% and V90% were larger in the FIF than in the PW plan.

Conclusions: The amount of change in dose parameters due to respiratory motion was smaller with the FIF technique than with irradiation using PWs, within an acceptable range.