Retrieved Cerebral Thrombi Studied by T2 and ADC Mapping: Preliminary results

  • Jernej Vidmar
  • Franci Bajd
  • Zoran Milošević
  • Igor Kocijančič
  • Igor Serša
  • Miran Jeromel


Object Recent advances in MRI technology makes it increasingly more competitive to CT also in the field of interventions. Multi-parametric MRI offers a significant amount of data relevant for characterization of human cerebral thrombi.

Materials and Methods Cerebral thrombi of 17 patients diagnosed with acute stroke were acquired by mechanical thrombectomy. The thrombi were subsequently scanned using a high spatial-resolution 3D T1-weighted MRI to obtain morphological characteristics of the thrombi and also by apparent diffusion coefficient (ADC) and transversal NMR relaxation time (T2) mapping. The MRI results were analyzed for possible correlations between thrombectomy procedure parameters (recanalization time and number of passes) and MR-measurable parameters (sample-mean ADC and T2, within-sample coefficient of variation of ADC and T2, and thrombus length).

Results Both MRI mapping techniques enabled a good discrimination among thrombi regions of different water mobility and compaction. Within-sample coefficient of variation of ADC was found most sensitive for discrimination between the thrombi where thrombectomy procedure was performed in a single pass and those where is was performed in two or more passes (p = 0.03). Interestingly, negative correlation was found between the recanalization time and thrombus length (ρ = -0.22).

Conclusion Preliminary results of presented study shows that pretreatment MRI assessment of thrombi in stroke patients could potentially ease stroke treatment planning. In this study it is shown that within-sample coefficient of variation of ADC could serve for perdition of possible complications during thrombectomy procedures.

How to Cite
Vidmar, J., Bajd, F., Milošević, Z., Kocijančič, I., Serša, I., & Jeromel, M. (2019). Retrieved Cerebral Thrombi Studied by T2 and ADC Mapping: Preliminary results. Radiology and Oncology, 53(4), 427-433. Retrieved from